Optic nerve head circulation in untreated ocular hypertension.
نویسندگان
چکیده
منابع مشابه
Optic nerve circulation and ocular pressure.
Rapid, short-lasting elevation of ocular pressure level produces simultaneous reduction in blood-flow rate in the distal 6 mm. of the extraocular portion of the optic nerve of the rhesus monkey as monitored by the heated thermocouple technique. The magnitude of this reduction was very small until intraocular pressure (IOP) exceeded 50 mm. Hg following which markedly and progressively greater re...
متن کاملEffects of nilvadipine, a calcium antagonist, on rabbit ocular circulation and optic nerve head circulation in NTG subjects.
PURPOSE To study the effects of nilvadipine, a Ca2+ antagonist, on tissue circulation in the optic nerve head (ONH), choroid, and retina in rabbits and on the ONH circulation in normal tension glaucoma (NTG) patients. METHODS Nilvadipine (3.2 microg/kg) or vehicle solution was injected intravenously into urethane-anesthetized rabbits, and the normalized blur value (NB), a quantitative index o...
متن کاملLaser scanning tomography of the optic nerve head in ocular hypertension and glaucoma.
BACKGROUND This study evaluated the ability of laser scanning tomography to distinguish between normal and glaucomatous optic nerve heads, and between glaucomatous subjects with and without field loss. METHODS 57 subjects were classified into three diagnostic groups: subjects with elevated intraocular pressure, normal optic nerve heads, and normal visual fields (n = 10); subjects with glaucom...
متن کاملOptic nerve damage in experimental mouse ocular hypertension.
PURPOSE To evaluate optic nerve damage in mice after laser-induced ocular hypertension. METHODS Ocular hypertension was induced unilaterally in 13 NIH Black Swiss mice by laser photocoagulation of the limbus. Over the following 12 weeks, intraocular pressure (IOP) was measured at regular intervals by the microneedle method. The optic nerves of these mice and of seven normal untreated mice wer...
متن کاملDetection of optic nerve damage in ocular hypertension.
Thirty patients with ocular hypertension were tested for contrast sensitivity loss. Seventeen were not on treatment, and thirteen were receiving some form of pressure reducing therapy. The contrast sensitivity results of 63% of ocular hypertensive eyes were abnormal (greater than 2 SDs from the age matched norm). Thus it appears that contrast sensitivity can detect early visual loss in patients...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1995
ISSN: 0007-1161
DOI: 10.1136/bjo.79.12.1088